The synergistic combination of Klamin® and AphaMax®
More Energy
Less Stress
Total Balance
What is Klamextra
KlamExtra® Nutrigea is a formulation that combines two patented extracts of the Klamath microalgae in a single formula: Klamin®, standardized in phenylethylamine (PEA), and AphaMax®, standardized in AFA-phycocyanins. 1,2
The combination was created to enhance the interaction between the two bioactive fractions, maintaining the natural complexity of the original algal matrix.
Properties
KlamExtra® has been studied in experimental models to evaluate the functional synergy between the two extractive fractions of the Klamath microalgae, with a specific focus on neurobiological and metabolic parameters 3,4
In the preclinical models analyzed, the scientific literature documents significant and consistent changes in markers associated with neuronal oxidative stress, also involved in the processes studied in the context of neurodegeneration, accompanied by modulations of parameters related to lipid metabolism and overall body composition. 4, 5
Furthermore, KlamExtra® has shown a positive effect in an in vivo study in reducing body weight, triglycerides, liver fat accumulation, and insulin resistance, promoting a more balanced and vital metabolic response. 4, 5
Our Flagship Nutrigea Product
KlamExtra® is not a simple sum of ingredients, but an advanced nutritional strategy based on extractive synergy, developed to fully exploit the potential of the Klamath microalgae in a single formulation.
BIBLIOGRAPHY
1 G D. Scoglio, et al., (2024). The commercial potential of Aphanizomenon flos-aquae, a nitrogen-fixing edible cyanobacterium, Journal of Applied Phycology, Volume 36, pages 1593-1617 (2024).
2 S. Scoglio, G D. Scoglio, (2024) Klamath Lake Aphanizomenon Flos-Aquae: Wild-Harvesting, Extracts and Benefits. Vol. Insights Into Algae – Fundamentals, Culture Techniques and Biotechnological Uses of Microalgae and Cyanobacteria.
3 Nuzzo D, Presti G, Picone P, Galizzi G, Gulotta E, Giuliano S, Mannino C, Gambino V, Scoglio S, Di Carlo M (2018) Effects of the Aphanizomenon flos-aquae extract (klamin®) on a neurodegeneration cellular model. Oxidat Med Cell Longev 2018:9089016.
4 Galizzi G, Deidda I, Amato A, Calvi P, Terzo S, Caruana L, Scoglio S, Mulè F, Di Carlo M (2023) Aphanizomenon flos-aquae (AFA) extract prevents neurodegeneration in the HFD mouse model by modulating astrocytes and microglia activation. Int J Mol Sci 24:4731
5 Terzo, S., Scoglio, S.; et al. (2023) Positive Impacts of Aphanizomenon Flos Aquae Extract on Obesity-Related Dysmetabolism in Mice with Diet-Induced Obesity. Cells